Exosomes are nano-scale extracellular vesicles (about one thousandth the size of a cell) - which are very small packages of signaling information. These exosome vesicles are like tiny bubbles filled with genetic information, proteins, cytokines, growth factors and messenger RNA that are released from cells in response to injury, inflammation and other disease processes like autoimmune disorders. As we age, the number and function of the Mesenchymal stem cells (MSC’s) in our tissues declines sharply. Our own aged progenitor cells in our body only produce about 30% of the cytokines and necessary growth factors compared with the young peri-natal Mesenchymal Stem cells (MSC’s). This substantial difference in the secretion of Exosomes from young peri-natal Mesenchymal Stem cells (MSC’s) offers a significant advantage over stem cells exosomes procured from the blood or tissue from your body.
At ReNUMD, our therapies use Exosome stem cells derived from the peri-natal Mesenchymal Stem cells (MSC’s) that contain billions of growth factors that can enhance the coordinated cascade of cellular and biochemical events involved in natural healing of injured tissues, healing, and skin rejuvenation/regeneration. Exosomes are protected from degradation by a liposomal membrane until they are delivered to the target cell.
Benefits of Exosome treatments
Yes, there are 3 types of exosome stem cells based on where they come from…. Amniotic fluid, Bone marrow (Hematopoietic), and connective tissue (Mesenchymal).
Mesenchymal stem cell (MSC) exosomes are unique type of exosomes that are produced by stem cells of the connective tissue lineage - the origin of skin, hair, bone, muscle, cartilage etc. MSC exosomes are very different than exosomes found an adult bone marrow, which has a preponderance of hematopoietic stem cell exosomes, or amniotic fluid, which has primarily maternal epithelial cell exosomes. The distinct ability of MSC exosomes to induce connective tissue synthesis may be the basis of many of the remarkable clinical benefits that have become observed with stem cell therapy.
Accelerate healing, tissue repair and reduce recovery time
Regenerate collagen in aging and damaged skin
Stimulate hair growth
Promotes cell repair and growth
Cell Regeneration including neurons
Improve Cell-to-Cell Signaling
At ReNUMD we only use XoGlo® Exosomes from Kimera labs.
XoGlo® is a purified mesenchymal stem cell (MSC)- derived exosome product that contains a multitude of growth factors that can enhance the coordinated cascade of cellular and biochemical events involved in natural healing and skin rejuvenation/regeneration.
The physiologic effects of the exosomal growth factors in XoGlo® can be used to stimulate the healing, regenerate collagen in aging and damaged skin, and reduce inflammation. XoGlo® has the potential to accelerate healing, improve skin texture, reduce scarring stimulate hair growth, and shorten recovery time after cosmetic procedures. XoGlo® is a cell-free isolate of MSC exosomes from a single donor. This concentrated biologic product is sterile – filtered and each millilitre of XoGlo® contains 1 billion MSC exosomes.